Positive UV exposure information

Bill · 09-24-2007, 09:25 AM

This question is for anyone out there that has studied vitamin D synthesis and has any thoughts on the matter.

1. Since 7-Dehydrocholesterol is the "precursor" of vitamin D (the substance in the blood that UV radiation converts into 25-Hydroxycalciferol)

2. 7-Dehydrocholesterol is one of the last "links of the chain" in the process of making cholesterol.

3. Once the body has sufficient 25-Hydroxycalciferol, it continues to act upon 7-Dehydrocholesterol, basically converting it to an inactive metabolite at which point it gets flushed out by the kidneys (?).

Why is there no talk of UV exposure even in higher doses than necessary for vitamin D production for the lowering of serum cholesterol?

Papa · 09-24-2007, 01:01 PM

Does it work? I would like to know!

All the cholesterol lowering drugs are wicked on the liver. I have high cholesterol and just now realize that I always had my physicals in spring when I have had the longest stretches of limited UV exposure.

Marca · 09-24-2007, 01:13 PM

Great question...!! I do not know the answer

Bill · 09-24-2007, 07:52 PM

Me either. That's why I asked it...

Sherin · 09-24-2007, 09:46 PM

Hmmmm. good question for Dr. John Cannell!

Bill · 09-30-2007, 02:57 PM

Bill · 10-01-2007, 10:04 AM

Ok. According to Dr. Holick's email that he sent to me this morning, it just doesn't work that way.

For one thing, I misstated the role of UV in creating 25(OH)D. It is converted by the liver, not by UV. The 7(OH)D IS acted upon by UV, I just said it wrong.

However, according to Dr. Holick, however, UV does not continue to act upon 7(OH)D as I had suggested in my question.

You can read more about how this DOES work here.

The latest from Dr. Holick Read the .pdf file for an accurate description of the process.

tanthis · 10-01-2007, 03:51 PM

thanks

09-24-2007, 09:25 AM	# 1
Bill Administrator, ITA supporter Join Date: Jul-30-2007 Member No.: 3 Gender: Posts: 17,811 Rep Power: 306601	An open question This question is for anyone out there that has studied vitamin D synthesis and has any thoughts on the matter. 1. Since 7-Dehydrocholesterol is the "precursor" of vitamin D (the substance in the blood that UV radiation converts into 25-Hydroxycalciferol) 2. 7-Dehydrocholesterol is one of the last "links of the chain" in the process of making cholesterol. 3. Once the body has sufficient 25-Hydroxycalciferol, it continues to act upon 7-Dehydrocholesterol, basically converting it to an inactive metabolite at which point it gets flushed out by the kidneys (?). Why is there no talk of UV exposure even in higher doses than necessary for vitamin D production for the lowering of serum cholesterol? __________________ If people would just stop and use their f'n brains, the world would be a better place! -Navigatin1 Philosopher, salon owner

09-24-2007, 01:13 PM	# 3
Marca President, European Operations, ITA supporter Join Date: Aug-01-2007 Location: Domaine de Romefort Member No.: 21 Gender: Posts: 12,937 My Mood: Rep Power: 21932	Great question...!! I do not know the answer __________________ www.DomainedeRomefort.com www.DiMarca-Online.com Donate to the ITA's Berman and Company campaign through UVTalk. *Click here*

09-24-2007, 07:52 PM	# 4
Bill Administrator, ITA supporter Join Date: Jul-30-2007 Member No.: 3 Gender: Posts: 17,811 Rep Power: 306601	Me either. That's why I asked it... __________________ If people would just stop and use their f'n brains, the world would be a better place! -Navigatin1 Philosopher, salon owner

09-24-2007, 09:46 PM	# 5
Sherin UVtalker Join Date: Jul-31-2007 Member No.: 15 Gender: Posts: 710 My Mood: Rep Power: 42	Hmmmm. good question for Dr. John Cannell! __________________ Some days it's not even worth chewing through the restraints!

09-30-2007, 02:57 PM	# 6
Bill Administrator, ITA supporter Join Date: Jul-30-2007 Member No.: 3 Gender: Posts: 17,811 Rep Power: 306601	__________________ If people would just stop and use their f'n brains, the world would be a better place! -Navigatin1 Philosopher, salon owner

09-24-2007, 01:01 PM	# 2
Papa WWCJD? Join Date: Sep-10-2007 Location: My house! Member No.: 80 Gender: Posts: 3,577 Rep Power: 36445	Does it work? I would like to know! All the cholesterol lowering drugs are wicked on the liver. I have high cholesterol and just now realize that I always had my physicals in spring when I have had the longest stretches of limited UV exposure.

10-01-2007, 10:04 AM	# 7
Bill Administrator, ITA supporter Join Date: Jul-30-2007 Member No.: 3 Gender: Posts: 17,811 Rep Power: 306601	Ok. According to Dr. Holick's email that he sent to me this morning, it just doesn't work that way. For one thing, I misstated the role of UV in creating 25(OH)D. It is converted by the liver, not by UV. The 7(OH)D IS acted upon by UV, I just said it wrong. However, according to Dr. Holick, however, UV does not continue to act upon 7(OH)D as I had suggested in my question. You can read more about how this DOES work here. The latest from Dr. Holick Read the .pdf file for an accurate description of the process. __________________ If people would just stop and use their f'n brains, the world would be a better place! -Navigatin1 Philosopher, salon owner

10-01-2007, 03:51 PM	# 8
tanthis Senior Member Join Date: Aug-13-2007 Location: waiting in line to see the baaaaabeeee Member No.: 45 Gender: MySpace ID: tanthis Posts: 7,142 My Mood: Rep Power: 43743	thanks

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