Positive UV exposure information

Bill · 05-30-2008, 07:50 PM

Geographic variation and risk of skin cancer in US women. Differences between melanoma, squamous cell carcinoma, and basal cell carcinoma.

Qureshi AA, Laden F, Colditz GA, Hunter DJ.
Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. aqureshi@partners.org
BACKGROUND: Occurrences of melanoma, squamous cell carcinoma (SCC), and basal cell carcinoma (BCC) have been associated with varying geography. Our goal was to evaluate differences in risk of these skin cancers according to residence at varying UV indices at 3 time points. METHODS: Prospective 1984-2002 study of 84 836 female nurses who lived in different UV index regions of the United States at birth and at 15 or 30 years of age. The outcome measure was diagnosis of melanoma, SCC, or BCC. RESULTS: During the 18-year study, 420 cases of melanoma, 863 cases of SCC, and 8215 cases of BCC occurred. At 30 years of age, age-adjusted risks for SCC were 1.47 (95% confidence interval [CI], 1.22-1.76) and 1.90 (95% CI, 1.51-2.36) for women residing in states with a UV index of 6 (medium) and 7 or more (high), respectively. Although elevated, the age-adjusted risk of BCC at 30 years of age associated with residence in these states was substantially less. Although the risk of melanoma was not elevated for women living in these states at 30 years of age, it was significantly elevated among women living in states with UV indices of 6 at birth and at 15 years of age. There was no material change in risk estimates with multivariate adjustment. For women who reported living in states with UV indices of 7 or more at all 3 time points, the multivariate risk of SCC was highest. CONCLUSIONS: The risk of SCC is independently affected by residence in locations with medium and high UV indices; the gradient of risk is weaker for BCC; and the risk of melanoma does not change significantly across this gradient.
PMID: 18332296 [PubMed - indexed for MEDLINE]

Bill · 05-30-2008, 07:54 PM

High UV index is a risk factor for squamous cell carcinoma, a mild risk factor for Basal cell carcinoma, but does not increase your risk of melanoma.

solarmeter · 05-31-2008, 11:03 AM

UV Index divided by 40 = erythemally effective UV (Eeff or Ery) in units of EAS weighted W/m².

So a UVI of 12 / 40 = 0.30 W/m² Ery. This is the maximum allowed dose rate for sunbeds in Europe as of June last year... the "EU Norm".

05-30-2008, 07:50 PM	# 1
Bill Administrator, ITA supporter Join Date: Jul-30-2007 Member No.: 3 Gender: Posts: 18,816 My Mood: Rep Power: 324997	UV index and skin cancers Geographic variation and risk of skin cancer in US women. Differences between melanoma, squamous cell carcinoma, and basal cell carcinoma. Qureshi AA, Laden F, Colditz GA, Hunter DJ. Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA. aqureshi@partners.org BACKGROUND: Occurrences of melanoma, squamous cell carcinoma (SCC), and basal cell carcinoma (BCC) have been associated with varying geography. Our goal was to evaluate differences in risk of these skin cancers according to residence at varying UV indices at 3 time points. METHODS: Prospective 1984-2002 study of 84 836 female nurses who lived in different UV index regions of the United States at birth and at 15 or 30 years of age. The outcome measure was diagnosis of melanoma, SCC, or BCC. RESULTS: During the 18-year study, 420 cases of melanoma, 863 cases of SCC, and 8215 cases of BCC occurred. At 30 years of age, age-adjusted risks for SCC were 1.47 (95% confidence interval [CI], 1.22-1.76) and 1.90 (95% CI, 1.51-2.36) for women residing in states with a UV index of 6 (medium) and 7 or more (high), respectively. Although elevated, the age-adjusted risk of BCC at 30 years of age associated with residence in these states was substantially less. Although the risk of melanoma was not elevated for women living in these states at 30 years of age, it was significantly elevated among women living in states with UV indices of 6 at birth and at 15 years of age. There was no material change in risk estimates with multivariate adjustment. For women who reported living in states with UV indices of 7 or more at all 3 time points, the multivariate risk of SCC was highest. CONCLUSIONS: The risk of SCC is independently affected by residence in locations with medium and high UV indices; the gradient of risk is weaker for BCC; and the risk of melanoma does not change significantly across this gradient. PMID: 18332296 [PubMed - indexed for MEDLINE] __________________ I didn't mean it. Please don't cry...

05-30-2008, 07:54 PM	# 2
Bill Administrator, ITA supporter Join Date: Jul-30-2007 Member No.: 3 Gender: Posts: 18,816 My Mood: Rep Power: 324997	High UV index is a risk factor for squamous cell carcinoma, a mild risk factor for Basal cell carcinoma, but does not increase your risk of melanoma. __________________ I didn't mean it. Please don't cry...

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05-31-2008, 11:03 AM	# 3
solarmeter UV Geek Squad Join Date: May-29-2008 Location: Lake St Clair Member No.: 235 Gender: Posts: 8 Rep Power: 0	UV Index divided by 40 = erythemally effective UV (Eeff or Ery) in units of EAS weighted W/m². So a UVI of 12 / 40 = 0.30 W/m² Ery. This is the maximum allowed dose rate for sunbeds in Europe as of June last year... the "EU Norm".